基于k-分辨-FB级数展开的多分量LFM信号分离

针对傅里叶-贝塞尔变换(FBT)难以估计和有效分离多分量LFM信号的问题,提出了一种k分辨-FB(k-FB)级数展开结合dechirp的信号分离与估计算法。在FB级数的基础上引入k分辨参数,通过理论推导,得出了信号频率与级数的关系,证明了参数估计精度与k取值正相关。通过解线频调和k-FB级数计算,实现了信号分离重构和参数估计。在不同信噪比、信号功率比和k分辨条件下对信号的分离精度进行了仿真研究,并与基于分数阶傅里叶变换(FrFT)的方法进行了对比。仿真结果验证了算法的有效性。     

Alternative exon usage selectively determines both tissue distribution and subcellular localization of the acyl-CoA thioesterase 7 gene products

Acyl-CoA thioesterases (ACOTs) catalyze the hydrolysis of acyl-CoAs to free fatty acids and coenzyme A. Recent studies have demonstrated that one gene named Acot7, reported to be mainly expressed in brain and testis, is transcribed in several different isoforms by alternative usage of first exons. Strongly decreased levels of ACOT7 activity and protein in both mitochondria and cytosol was reported in patients diagnosed with fatty acid oxidation defects, linking ACOT7 function to regulation of fatty acid oxidation in other tissues. In this study, we have identified five possible first exons in mouse Acot7 (Acot7a–e) and show that all five first exons are transcribed in a tissue-specific manner. Taken together, these data show that the Acot7 gene is expressed as multiple isoforms in a tissue-specific manner, and that expression in tissues other than brain and testis is likely to play important roles in fatty acid metabolism. Received 5 February 2007: received after revision 3 April 2007; accepted 19 April 2007     

纳洛酮对大鼠脑外伤后神经细胞凋亡的影响

目的：采用Feeney法自由落体撞击脑损伤动物模型，观察纳洛酮对脑外伤后神经细胞凋亡和脑水肿的影响。方法：90只大鼠分为实验组及对照组，在损伤后15、60min及24h分别予纳洛酮或生理盐水，损伤后第5d断头处死大鼠，TUNEL法测定神经细胞原位凋亡情况，测定损伤侧大脑半球含水理以及光镜下观察细胞形态学改变。结果：与对照组比较，大鼠脑外伤后15及60min静注纳洛酮可保护神经细胞，减少凋亡率，减轻脑水肿；而外伤后24h给药，神经细胞凋亡率以及脑水肿无显著性差异。结论；研究结果提示纳洛酮作为阿片受体的拮抗剂有保护大鼠脑外伤后神经细胞的作用，但应在外伤后尽早用药。     

浅谈中小医院如何留住人才

分析了中小医院人才流失的影响因素,探讨了人才流动的心理特点,在此基础上提出了避免人才流失的一些策略。     

浅谈提高企业员工素质

该文从提高员工的素质是面对新世纪的客观要求、提高员工素质与煤矿企业的、工作机制、社会环境及经济效益的关系、提高员工的素质,要加强对职工的培训、加强对人才工作的管理,防止人才流失四个方面阐述了如何提高企业员工素质,具有一定借鉴意义。     

浅议医院人才流失与劳动合同管理

分析了人才流失给医院造成的损失,指出加强劳动合同管理、实行劳动合同制约对控制和减少医院人才流失具有一定的作用。     

Inhibition by tetanus and botulinum A toxin of the release of [3H]noradrenaline and [3H]GABA from rat brain homogenate

Summary Rat brain homogenate was preloaded with [³H]noradrenaline or [³H]GABA and stimulated with high K⁺. Tetanus toxin and botulinum A neurotoxin partially prevent the evoked [³H]noradrenaline release in the same range of toxin concentrations starting below 10^–10M. In contrast, release of -amino butyric acid (GABA) is much more sensitive to tetanus than to botulinum A toxin.     

MRI表现在脑胶质瘤恶性度诊断中的作用

本文比较了１０７例脑胶质瘤的病理分级与磁共振影像表现,结果显示两者之间有密切的关系（Ｐ＜０００５）。高度恶性胶质瘤中,ＭＲＩ诊断正确率为８８１０％,而低度恶性胶质瘤中为６４６２％（Ｐ＜０００５）。各单项ＭＲＩ表现,如病灶强化程度、瘤周水肿程度、囊变、坏死等在高或低度恶性胶质瘤中出现率无明显差异（Ｐ值均大于００５）。表明ＭＲＩ表现可在很大程度上反映脑胶质瘤的恶性程度,但在低度恶性胶质瘤中,易出现“过诊断现象”。     

脑信息特征的评价分类方法

对脑信息处理的能力特征量和总体偏离度特征量进行了确定性评价分类.在分类数上,提出了common分类法,以一般人的特征作为分类基准,在common两边展开,以确定分类数.在分类边界上,提出了根据特征量的正态分布确定分类边界的方法.若特征量分布不是正态分布,则采用了博克斯和考克斯变换将其变为正态分布,最终得到能力特征量和总体偏离度特征量的分类规则.由于人的行为是脑信息处理在宏观上的表现,所以其研究成果可直接用来评价人的能力和行为特征.     

Classification of Medical Brain Images

Since brain tumors endanger people‘s living quality and even their lives, the accuracy of classification becomes more important. Conventional classifying techniques are used to deal with thosedatasets with characters and numbers. It is difficult, however, to apply them to datasets that include brain images and medical history (alphanumeric data), especially to guarantee the accuracy.For these datasets, this paper combines the knowledge of medical field and improves the traditional decision tree. The new classification algorithm with the direction of the medical knowledge not only adds the interaction with the doctors, but also enhances the quality of classification. The algorithm has been used on real brain CT images and a precious rule has been gained from the experiments. This oaoer shows that the ahzorithm works well for real CT data.